Hypothesized behavioral host manipulation by SARS-CoV2 / COVID-19 infection
Identifieur interne : 000441 ( Main/Exploration ); précédent : 000440; suivant : 000442Hypothesized behavioral host manipulation by SARS-CoV2 / COVID-19 infection
Auteurs : Michael C. Barton [États-Unis] ; Kaylee V. Bennett [États-Unis] ; John R. Cook [États-Unis] ; Gordon G. Gallup [États-Unis] ; Steven M. Platek [États-Unis]Source :
- Medical Hypotheses [ 0306-9877 ] ; 2020.
Abstract
Although not widely studied, behavioral host manipulation by various pathogens has been documented. Host manipulation is the process by which a pathogen evolves adaptations to manipulate the behavior of the host to maximize reproduction (Ro) of the pathogen. The most notable example is rabies. When a host is infected with the rabies virus it gets into the host’s central nervous system and triggers hyper aggression. The virus is also present in the rabid animal’s saliva so being bitten transmits the infection to a new host and the old host is left to eventually die if untreated. Toxoplasmosis is another example. When mice are infected they demonstrate a fearlessness toward cats, thus increasing their chances of being eaten. Toxoplasmosis needs the digestive tract of the feline to survive. Recent studies have shown that exposure to toxoplasmosis in humans (e.g., through cat feces) has also been associated with behavioral changes that are predicted to enhance the spread of the pathogen. Even the common influenza virus has been shown to selectively increase in-person sociality during the 48-hour incubation period, thus producing an obvious vector for transmission. Here we hypothesize that the novel coronavirus, SARS-CoV2, which produces the COVID-19 disease may produce similar host manipulations that maximize its transmission between humans.
Url:
DOI: 10.1016/j.mehy.2020.109750
PubMed: NONE
PubMed Central: 7175891
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000770
- to stream Pmc, to step Curation: 000770
- to stream Pmc, to step Checkpoint: 000372
- to stream Ncbi, to step Merge: 001338
- to stream Ncbi, to step Curation: 001338
- to stream Ncbi, to step Checkpoint: 001338
- to stream Main, to step Merge: 000441
- to stream Main, to step Curation: 000441
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Hypothesized behavioral host manipulation by SARS-CoV2 / COVID-19 infection</title><author><name sortKey="Barton, Michael C" sort="Barton, Michael C" uniqKey="Barton M" first="Michael C." last="Barton">Michael C. Barton</name><affiliation wicri:level="2"><nlm:aff id="af005">Georgia Gwinnett College, Lawrenceville, GA 30024 USA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Géorgie (États-Unis)</region></placeName><wicri:cityArea>Georgia Gwinnett College, Lawrenceville</wicri:cityArea></affiliation></author><author><name sortKey="Bennett, Kaylee V" sort="Bennett, Kaylee V" uniqKey="Bennett K" first="Kaylee V." last="Bennett">Kaylee V. Bennett</name><affiliation wicri:level="2"><nlm:aff id="af005">Georgia Gwinnett College, Lawrenceville, GA 30024 USA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Géorgie (États-Unis)</region></placeName><wicri:cityArea>Georgia Gwinnett College, Lawrenceville</wicri:cityArea></affiliation></author><author><name sortKey="Cook, John R" sort="Cook, John R" uniqKey="Cook J" first="John R." last="Cook">John R. Cook</name><affiliation wicri:level="2"><nlm:aff id="af005">Georgia Gwinnett College, Lawrenceville, GA 30024 USA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Géorgie (États-Unis)</region></placeName><wicri:cityArea>Georgia Gwinnett College, Lawrenceville</wicri:cityArea></affiliation></author><author><name sortKey="Gallup, Gordon G" sort="Gallup, Gordon G" uniqKey="Gallup G" first="Gordon G." last="Gallup">Gordon G. Gallup</name><affiliation wicri:level="2"><nlm:aff id="af010">University at Albany-SUNY, Albany, NY, 12222 USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>University at Albany-SUNY, Albany, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Platek, Steven M" sort="Platek, Steven M" uniqKey="Platek S" first="Steven M." last="Platek">Steven M. Platek</name><affiliation wicri:level="2"><nlm:aff id="af005">Georgia Gwinnett College, Lawrenceville, GA 30024 USA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Géorgie (États-Unis)</region></placeName><wicri:cityArea>Georgia Gwinnett College, Lawrenceville</wicri:cityArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmc">7175891</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175891</idno><idno type="RBID">PMC:7175891</idno><idno type="doi">10.1016/j.mehy.2020.109750</idno><idno type="pmid">NONE</idno><date when="2020">2020</date><idno type="wicri:Area/Pmc/Corpus">000770</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000770</idno><idno type="wicri:Area/Pmc/Curation">000770</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000770</idno><idno type="wicri:Area/Pmc/Checkpoint">000372</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000372</idno><idno type="wicri:Area/Ncbi/Merge">001338</idno><idno type="wicri:Area/Ncbi/Curation">001338</idno><idno type="wicri:Area/Ncbi/Checkpoint">001338</idno><idno type="wicri:doubleKey">0306-9877:2020:Barton M:hypothesized:behavioral:host</idno><idno type="wicri:Area/Main/Merge">000441</idno><idno type="wicri:Area/Main/Curation">000441</idno><idno type="wicri:Area/Main/Exploration">000441</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Hypothesized behavioral host manipulation by SARS-CoV2 / COVID-19 infection</title><author><name sortKey="Barton, Michael C" sort="Barton, Michael C" uniqKey="Barton M" first="Michael C." last="Barton">Michael C. Barton</name><affiliation wicri:level="2"><nlm:aff id="af005">Georgia Gwinnett College, Lawrenceville, GA 30024 USA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Géorgie (États-Unis)</region></placeName><wicri:cityArea>Georgia Gwinnett College, Lawrenceville</wicri:cityArea></affiliation></author><author><name sortKey="Bennett, Kaylee V" sort="Bennett, Kaylee V" uniqKey="Bennett K" first="Kaylee V." last="Bennett">Kaylee V. Bennett</name><affiliation wicri:level="2"><nlm:aff id="af005">Georgia Gwinnett College, Lawrenceville, GA 30024 USA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Géorgie (États-Unis)</region></placeName><wicri:cityArea>Georgia Gwinnett College, Lawrenceville</wicri:cityArea></affiliation></author><author><name sortKey="Cook, John R" sort="Cook, John R" uniqKey="Cook J" first="John R." last="Cook">John R. Cook</name><affiliation wicri:level="2"><nlm:aff id="af005">Georgia Gwinnett College, Lawrenceville, GA 30024 USA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Géorgie (États-Unis)</region></placeName><wicri:cityArea>Georgia Gwinnett College, Lawrenceville</wicri:cityArea></affiliation></author><author><name sortKey="Gallup, Gordon G" sort="Gallup, Gordon G" uniqKey="Gallup G" first="Gordon G." last="Gallup">Gordon G. Gallup</name><affiliation wicri:level="2"><nlm:aff id="af010">University at Albany-SUNY, Albany, NY, 12222 USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>University at Albany-SUNY, Albany, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Platek, Steven M" sort="Platek, Steven M" uniqKey="Platek S" first="Steven M." last="Platek">Steven M. Platek</name><affiliation wicri:level="2"><nlm:aff id="af005">Georgia Gwinnett College, Lawrenceville, GA 30024 USA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Géorgie (États-Unis)</region></placeName><wicri:cityArea>Georgia Gwinnett College, Lawrenceville</wicri:cityArea></affiliation></author></analytic><series><title level="j">Medical Hypotheses</title><idno type="ISSN">0306-9877</idno><idno type="eISSN">1532-2777</idno><imprint><date when="2020">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Although not widely studied, behavioral host manipulation by various pathogens has been documented. Host manipulation is the process by which a pathogen evolves adaptations to manipulate the behavior of the host to maximize reproduction (R<sub>o</sub>) of the pathogen. The most notable example is rabies. When a host is infected with the rabies virus it gets into the host’s central nervous system and triggers hyper aggression. The virus is also present in the rabid animal’s saliva so being bitten transmits the infection to a new host and the old host is left to eventually die if untreated. Toxoplasmosis is another example. When mice are infected they demonstrate a fearlessness toward cats, thus increasing their chances of being eaten. Toxoplasmosis needs the digestive tract of the feline to survive. Recent studies have shown that exposure to toxoplasmosis in humans (e.g., through cat feces) has also been associated with behavioral changes that are predicted to enhance the spread of the pathogen. Even the common influenza virus has been shown to selectively increase in-person sociality during the 48-hour incubation period, thus producing an obvious vector for transmission. Here we hypothesize that the novel coronavirus, SARS-CoV2, which produces the COVID-19 disease may produce similar host manipulations that maximize its transmission between humans.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Herbison, R" uniqKey="Herbison R">R. Herbison</name></author><author><name sortKey="Lagrue, C" uniqKey="Lagrue C">C. Lagrue</name></author><author><name sortKey="Poulin, R" uniqKey="Poulin R">R. Poulin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Johnson, K V A" uniqKey="Johnson K">K.V.-A. Johnson</name></author><author><name sortKey="Foster, K R" uniqKey="Foster K">K.R. Foster</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Poletti, P" uniqKey="Poletti P">P. Poletti</name></author><author><name sortKey="Visintainer, R" uniqKey="Visintainer R">R. Visintainer</name></author><author><name sortKey="Lepri, B" uniqKey="Lepri B">B. Lepri</name></author><author><name sortKey="Merler, S" uniqKey="Merler S">S. Merler</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Reiber, C" uniqKey="Reiber C">C. Reiber</name></author><author><name sortKey="Schattuck, E C" uniqKey="Schattuck E">E.C. Schattuck</name></author><author><name sortKey="Fiore, S" uniqKey="Fiore S">S. Fiore</name></author><author><name sortKey="Alperin, P" uniqKey="Alperin P">P. Alperin</name></author><author><name sortKey="Davis, V" uniqKey="Davis V">V. Davis</name></author><author><name sortKey="Moore, J" uniqKey="Moore J">J. Moore</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Severance, E G" uniqKey="Severance E">E.G. Severance</name></author><author><name sortKey="Dickerson, F B" uniqKey="Dickerson F">F.B. Dickerson</name></author><author><name sortKey="Viscidi, R P" uniqKey="Viscidi R">R.P. Viscidi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sugden, K" uniqKey="Sugden K">K. Sugden</name></author><author><name sortKey="Moffitt, T E" uniqKey="Moffitt T">T.E. Moffitt</name></author><author><name sortKey="Pinto, L" uniqKey="Pinto L">L. Pinto</name></author><author><name sortKey="Poulton, R" uniqKey="Poulton R">R. Poulton</name></author><author><name sortKey="Williams, B S" uniqKey="Williams B">B.S. Williams</name></author><author><name sortKey="Caspi, A" uniqKey="Caspi A">A. Caspi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Algahtani, H" uniqKey="Algahtani H">H. Algahtani</name></author><author><name sortKey="Subahi, A" uniqKey="Subahi A">A. Subahi</name></author><author><name sortKey="Shirah, B" uniqKey="Shirah B">B. Shirah</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, Y C" uniqKey="Li Y">Y.-C. Li</name></author><author><name sortKey="Bai, W Z" uniqKey="Bai W">W.-Z. Bai</name></author><author><name sortKey="Hashikawa, T" uniqKey="Hashikawa T">T. Hashikawa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Carvalho, P M M" uniqKey="Carvalho P">P.M.M. Carvalho</name></author><author><name sortKey="Moreira, M M" uniqKey="Moreira M">M.M. Moreira</name></author><author><name sortKey="Oliveira, M N A" uniqKey="Oliveira M">M.N.A. Oliveira</name></author><author><name sortKey="Landim, J M M" uniqKey="Landim J">J.M.M. Landim</name></author><author><name sortKey="Neto, M L R" uniqKey="Neto M">M.L.R. Neto</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Xiang, Y T" uniqKey="Xiang Y">Y.T. Xiang</name></author><author><name sortKey="Yang, Y" uniqKey="Yang Y">Y. Yang</name></author><author><name sortKey="Li, W" uniqKey="Li W">W. Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Eisenberger, N I" uniqKey="Eisenberger N">N.I. Eisenberger</name></author><author><name sortKey="Lieberman, M D" uniqKey="Lieberman M">M.D. Lieberman</name></author><author><name sortKey="Williams, K D" uniqKey="Williams K">K.D. Williams</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Krill, A L" uniqKey="Krill A">A.L. Krill</name></author><author><name sortKey="Platek, S M" uniqKey="Platek S">S.M. Platek</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gamucci, A" uniqKey="Gamucci A">A. Gamucci</name></author><author><name sortKey="Uccella, S" uniqKey="Uccella S">S. Uccella</name></author><author><name sortKey="Sciarretta, L" uniqKey="Sciarretta L">L. Sciarretta</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hu, X" uniqKey="Hu X">X. Hu</name></author><author><name sortKey="Chen, D" uniqKey="Chen D">D. Chen</name></author><author><name sortKey="Wu, L" uniqKey="Wu L">L. Wu</name></author><author><name sortKey="He, G" uniqKey="He G">G. He</name></author><author><name sortKey="Ye, W" uniqKey="Ye W">W. Ye</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huang, T L" uniqKey="Huang T">T.L. Huang</name></author><author><name sortKey="Wu, S C" uniqKey="Wu S">S.C. Wu</name></author><author><name sortKey="Chiang, Y S" uniqKey="Chiang Y">Y.S. Chiang</name></author><author><name sortKey="Chen, J F" uniqKey="Chen J">J.F. Chen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Izumoto, Y" uniqKey="Izumoto Y">Y. Izumoto</name></author><author><name sortKey="Inoue, S" uniqKey="Inoue S">S. Inoue</name></author><author><name sortKey="Yasuda, N" uniqKey="Yasuda N">N. Yasuda</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mednick, S A" uniqKey="Mednick S">S.A. Mednick</name></author><author><name sortKey="Machon, R A" uniqKey="Machon R">R.A. Machon</name></author><author><name sortKey="Huttunen, M O" uniqKey="Huttunen M">M.O. Huttunen</name></author><author><name sortKey="Bonett, D" uniqKey="Bonett D">D. Bonett</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gullien Grima, F G" uniqKey="Gullien Grima F">F.G. Gullien-Grima</name></author><author><name sortKey="Brugos Larumbe, A" uniqKey="Brugos Larumbe A">A. Brugos-Larumbe</name></author><author><name sortKey="Guillen Aguinaga, S" uniqKey="Guillen Aguinaga S">S. Guillen-Aguinaga</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tang, X" uniqKey="Tang X">X. Tang</name></author><author><name sortKey="Wu, C" uniqKey="Wu C">C. Wu</name></author><author><name sortKey="Li, X" uniqKey="Li X">X. Li</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Géorgie (États-Unis)</li><li>État de New York</li></region></list><tree><country name="États-Unis"><region name="Géorgie (États-Unis)"><name sortKey="Barton, Michael C" sort="Barton, Michael C" uniqKey="Barton M" first="Michael C." last="Barton">Michael C. Barton</name></region><name sortKey="Bennett, Kaylee V" sort="Bennett, Kaylee V" uniqKey="Bennett K" first="Kaylee V." last="Bennett">Kaylee V. Bennett</name><name sortKey="Cook, John R" sort="Cook, John R" uniqKey="Cook J" first="John R." last="Cook">John R. Cook</name><name sortKey="Gallup, Gordon G" sort="Gallup, Gordon G" uniqKey="Gallup G" first="Gordon G." last="Gallup">Gordon G. Gallup</name><name sortKey="Platek, Steven M" sort="Platek, Steven M" uniqKey="Platek S" first="Steven M." last="Platek">Steven M. Platek</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/StressCovidV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000441 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000441 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= StressCovidV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:7175891
|texte= Hypothesized behavioral host manipulation by SARS-CoV2 / COVID-19 infection
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:NONE" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a StressCovidV1
| This area was generated with Dilib version V0.6.33. |  |